Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dao.3D-amino-acid oxidase, tandem duplicate 3. (353 aa)    
Predicted Functional Partners:
hoga1
4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Catalyzes the final step in the metabolic pathway of hydroxyproline.
   
 
 0.902
hao1
Hydroxyacid oxidase (glycolate oxidase) 1.
   
 
 0.901
pycr3
Pyrroline-5-carboxylate reductase 3; Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline.
  
 
 0.891
p4ha1a
Prolyl 4-hydroxylase, alpha polypeptide I a.
     
 0.877
zgc:92040
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
  
 
 0.872
sardh
Sarcosine dehydrogenase.
  
 0.870
agxtb
Serine--pyruvate aminotransferase.
  
 
 0.868
agxta
Serine--pyruvate aminotransferase.
  
 
 0.868
pipox
Pipecolic acid oxidase.
   
 
 0.867
hao2
Hydroxyacid oxidase 2 (long chain).
   
 
 0.864
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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