STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppm1fProtein phosphatase, Mg2+/Mn2+-dependent, 1F. (424 aa)    
Predicted Functional Partners:
ascc2
Activating signal cointegrator 1 complex subunit 2.
      
 0.882
crnkl1
Crooked neck pre-mRNA-splicing factor 1.
   
  
 0.881
ess2
Ess-2-splicing factor homolog.
   
  
 0.859
kansl2
KAT8 regulatory NSL complex subunit 2.
   
  
 0.853
dgcr2
DiGeorge syndrome critical region gene 2.
      
 0.848
prcc
Proline-rich mitotic checkpoint control factor.
      
 0.843
prpf19
PRP19/PSO4 homolog (S. cerevisiae).
   
  
 0.766
xab2
Similar to Xab2 protein.
      
 0.755
med15
Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol [...]
      
 0.743
snw1
SNW domain-containing 1.
      
 0.695
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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