STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfc5Replication factor C (activator 1) 5. (334 aa)    
Predicted Functional Partners:
rfc2
Replication factor C (activator 1) 2.
   
0.999
rfc1
Replication factor C subunit 1.
   
0.999
rfc4
Replication factor C (activator 1) 4.
  
0.999
rfc3
Replication factor C (Activator 1) 3.
   
0.999
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.997
atad5b
ATPase family AAA domain-containing 5b.
   
 0.995
rad17
RAD17 checkpoint clamp loader component.
    
 0.994
dscc1
Sister chromatid cohesion protein DCC1; Loads pcna onto primed templates regulating velocity, spacing and restart activity of replication forks. May couple DNA replication to sister chromatid cohesion (By similarity).
   
 
 0.993
chtf8
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae).
   
 
 0.990
chtf18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae).
   
 
 0.989
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.