Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
irx4aIroquois homeobox protein 4a. (440 aa)    
Predicted Functional Partners:
irx1a
Iroquois homeobox protein 1, a.
   
 
0.762
mkxa
Homeobox protein mohawk A.
    
 
 0.687
nme2a
Nucleoside diphosphate kinase.
      
 0.681
p2rx1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
      
 0.662
irx1b
Iroquois homeobox protein 1, b.
   
 
 0.657
barhl2
BarH-class homeodomain transcription factor.
   
 
 0.637
irx2a
Iroquois homeobox 2a.
   
  
0.616
lmo4b
LIM domain only 4, like.
    
 
 0.614
sez6a
Seizure-related 6 homolog a.
    
 
 0.595
nppa
Natriuretic peptide A.
      
 0.575
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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