Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
cdkn2aipCDKN2A-interacting protein. (312 aa)    
Predicted Functional Partners:
xrn2
5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.
    
 
 0.992
cdkn2a/b
Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).
    
 
 0.776
tpra
Translocated promoter region a, nuclear basket protein.
    
 
 0.749
ptmaa
Prothymosin alpha-A.
   
 
 0.673
trappc11
Trafficking protein particle complex subunit 11; Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
      
 0.645
tmem145
Transmembrane protein 145.
      
 0.645
mdm2
E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.
    
 
 0.644
mrps33
Mitochondrial ribosomal protein S33.
    
   0.629
mphosph6
M-phase phosphoprotein 6.
      
 0.622
cirbpa
Cold-inducible RNA-binding protein a.
    
 
 0.612
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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