STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cnn2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (307 aa)    
Predicted Functional Partners:
acta1b
Actin alpha 1, skeletal muscle b.
   
 
 0.974
utrn
Utrophin; May play a role in anchoring the cytoskeleton to the plasma membrane.
      
 0.845
wdr90
WD repeat domain 90.
    
 
 0.792
plecb
Plectin b.
   
  
 0.772
myh11a
Myosin, heavy polypeptide 11, smooth muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  
 0.766
syne1a
Spectrin repeat-containing, nuclear envelope 1a.
      
 0.758
syne1b
Spectrin repeat-containing, nuclear envelope 1b.
      
 0.758
pleca
Plectin a.
   
  
 0.750
pls3
Plastin 3 (T isoform).
   
 
 0.688
ift81
Intraflagellar transport 81 homolog.
      
 0.679
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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