Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
syncSyncoilin, intermediate filament protein. (451 aa)    
Predicted Functional Partners:
synm
Synemin, intermediate filament protein; Belongs to the intermediate filament family.
    
 0.748
sncgb
Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family.
    
 
 0.615
gale
UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
      
 0.614
mtmr14
Myotubularin-related protein 14.
      
 0.611
mtr
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
      
 0.604
zgc:193505
Zgc:193505.
    
 
 0.491
sncga
Synuclein, gamma a; Belongs to the synuclein family.
    
 
 0.491
prph
Prph protein; Belongs to the intermediate filament family.
   
  0.472
sncb
Beta-synuclein; Belongs to the synuclein family.
      
 0.465
dtna
Dystrobrevin.
    
 
 0.457
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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