Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pitpnbPhosphatidylinositol transfer protein, beta. (272 aa)    
Predicted Functional Partners:
pitpnm3
PITPNM family member 3.
 
    
 0.901
plrdgb
PITP-less RdgB-like protein.
 
      0.900
olfml2ba
Olfactomedin-like 2Ba.
      
 0.881
pcnx1
Pecanex 1.
      
 0.839
mvb12bb
Multivesicular body subunit 12Bb.
      
 0.829
sgsm2
Small G protein-signaling modulator 2.
      
 0.800
golga1
Golgin A1.
   
  
 0.720
golph3l
Golgi phosphoprotein 3-like.
      
 0.695
sp8b
Transcription factor Sp8; Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos. Belongs to the Sp1 C2H2-type zinc-finger protein family.
   
 0.677
viml
Vimentin-like; Belongs to the intermediate filament family.
      
 0.669
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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