STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
f2Coagulation factor II (thrombin); Belongs to the peptidase S1 family. (635 aa)    
Predicted Functional Partners:
serpinc1
Serine (Or cysteine) proteinase inhibitor, clade C (Antithrombin), member 1; Belongs to the serpin family.
   
 0.999
fga
Fibrinogen alpha chain.
   
 0.996
serpind1
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.
   
 0.995
fgb
Fibrinogen, B beta polypeptide.
   
 0.989
fgg
Fibrinogen, gamma polypeptide.
   
 0.988
f3a
Coagulation factor IIIa.
    
 
 0.983
serpine2
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family.
    
 0.968
F2RL3
Si:ch211-132p1.2; Belongs to the G-protein coupled receptor 1 family.
    
 0.963
thbd
Thrombomodulin.
    
 
 0.960
f5
Coagulation factor V; Belongs to the multicopper oxidase family.
   
 0.952
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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