Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
znf408Zinc finger protein 408. (764 aa)    
Predicted Functional Partners:
tspan12
Tetraspanin.
      
 0.964
gpatch3
G patch domain-containing 3.
   
    0.962
rcbtb1
Regulator of chromosome condensation (RCC1) and BTB (POZ) domain-containing protein 1.
    
 0.893
kif11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 
 0.884
ndp
Norrin cystine knot growth factor NDP.
    
 
 0.858
samd11
Sterile alpha motif domain-containing 11.
    
 
 0.856
fzd4
Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 
 0.832
lrp5
Low density lipoprotein receptor-related protein 5.
    
 0.727
ccnj
Cyclin J; Belongs to the cyclin family.
    
 
 0.637
mfsd5
Molybdate-anion transporter; Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum; Belongs to the major facilitator superfamily.
   
  
 0.612
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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