Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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traddTumor necrosis factor receptor type 1-associated DEATH domain protein; Adapter molecule for tnfrsf1a that specifically associates with the cytoplasmic domain of activated tnfrsf1a mediating its interaction with fadd. (293 aa)    
Predicted Functional Partners:
tnfrsf1a
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.999
ripk1l
Receptor (TNFRSF)-interacting serine-threonine kinase 1,-like.
    
 0.999
fadd
Fas (tnfrsf6)-associated via death domain.
   
 0.999
casp8
Caspase 8, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
 0.998
traf2b
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.997
traf2a
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.996
birc2
Baculoviral IAP repeat-containing 2.
   
 0.995
casp10
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
 0.994
tnfb
Tumor necrosis factor b (TNF superfamily, member 2).
    
 
 0.991
traf1
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.991
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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