Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cebpgCCAAT/enhancer binding protein (C/EBP), gamma. (163 aa)    
Predicted Functional Partners:
cebpb
CCAAT/enhancer-binding protein.
   
0.972
ddit3
DNA-damage-inducible transcript 3.
   
 
 0.970
atf5a
Activating transcription factor 5a.
   
 0.966
atf4a
Cyclic AMP-dependent transcription factor ATF-4; Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. May play a role in the regulation of the circadian clock (By similarity).
   
 0.947
atf3
Activating transcription factor 3.
   
 
 0.932
ciita
Class II, major histocompatibility complex, transactivator.
     
  0.909
atf4b
Activating transcription factor 4b.
   
 0.847
traf6
TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction.
    
 0.825
mllt10
MLLT10 histone lysine methyltransferase DOT1L cofactor.
    
   0.773
fosab
V-fos FBJ murine osteosarcoma viral oncogene homolog Ab.
    
 
 0.758
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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