Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
heatr3HEAT repeat-containing 3. (682 aa)    
Predicted Functional Partners:
tsr2
Pre-rRNA-processing protein TSR2 homolog; May be involved in 20S pre-rRNA processing.
   
  
 0.814
tmem186
Transmembrane protein 186.
    
   0.771
ca7
Carbonic anhydrase VII; Belongs to the alpha-carbonic anhydrase family.
 
    
 0.769
gtdc1
Glycosyltransferase-like domain-containing protein 1; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
      
 0.711
cnep1r1
Nuclear envelope phosphatase-regulatory subunit 1; May form with the serine/threonine protein phosphatase ctdnep1 an active complex dephosphorylating and activating lipins. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol [...]
   
  
 0.706
C2H14orf119
Si:ch211-14a17.11.
      
 0.703
znf592
Zinc finger protein 592.
   
  
 0.691
rpf2
Ribosome production factor 2 homolog.
   
 
 0.671
PSMD4
Proteasome 26S subunit, non-ATPase 4.
      
 0.638
psmd4a
Proteasome 26S subunit, non-ATPase 4a.
      
 0.638
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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