| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gins1 | gins3 | ENSDARP00000017647 | ENSDARP00000056722 | GINS complex subunit 1 (Psf1 homolog). | GINS complex subunit 3. | 0.999 |
| gins1 | gins4 | ENSDARP00000017647 | ENSDARP00000151126 | GINS complex subunit 1 (Psf1 homolog). | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | 0.999 |
| gins1 | mcm2 | ENSDARP00000017647 | ENSDARP00000133012 | GINS complex subunit 1 (Psf1 homolog). | DNA helicase; Belongs to the MCM family. | 0.976 |
| gins1 | mcm7 | ENSDARP00000017647 | ENSDARP00000132487 | GINS complex subunit 1 (Psf1 homolog). | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.968 |
| gins1 | rpa1 | ENSDARP00000017647 | ENSDARP00000029067 | GINS complex subunit 1 (Psf1 homolog). | Replication protein A 70 kDa DNA-binding subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.581 |
| gins1 | timeless | ENSDARP00000017647 | ENSDARP00000099210 | GINS complex subunit 1 (Psf1 homolog). | Timeless circadian clock. | 0.910 |
| gins1 | tipin | ENSDARP00000017647 | ENSDARP00000052473 | GINS complex subunit 1 (Psf1 homolog). | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be required fin the replication checkpoint induced by hydroxyurea or ultraviolet light (By similarity). | 0.978 |
| gins1 | wdhd1 | ENSDARP00000017647 | ENSDARP00000113096 | GINS complex subunit 1 (Psf1 homolog). | WD repeat and HMG-box DNA-binding protein 1. | 0.936 |
| gins3 | gins1 | ENSDARP00000056722 | ENSDARP00000017647 | GINS complex subunit 3. | GINS complex subunit 1 (Psf1 homolog). | 0.999 |
| gins3 | gins4 | ENSDARP00000056722 | ENSDARP00000151126 | GINS complex subunit 3. | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | 0.999 |
| gins3 | mcm2 | ENSDARP00000056722 | ENSDARP00000133012 | GINS complex subunit 3. | DNA helicase; Belongs to the MCM family. | 0.987 |
| gins3 | mcm7 | ENSDARP00000056722 | ENSDARP00000132487 | GINS complex subunit 3. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.984 |
| gins3 | timeless | ENSDARP00000056722 | ENSDARP00000099210 | GINS complex subunit 3. | Timeless circadian clock. | 0.982 |
| gins3 | tipin | ENSDARP00000056722 | ENSDARP00000052473 | GINS complex subunit 3. | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be required fin the replication checkpoint induced by hydroxyurea or ultraviolet light (By similarity). | 0.980 |
| gins3 | wdhd1 | ENSDARP00000056722 | ENSDARP00000113096 | GINS complex subunit 3. | WD repeat and HMG-box DNA-binding protein 1. | 0.944 |
| gins4 | gins1 | ENSDARP00000151126 | ENSDARP00000017647 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | GINS complex subunit 1 (Psf1 homolog). | 0.999 |
| gins4 | gins3 | ENSDARP00000151126 | ENSDARP00000056722 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | GINS complex subunit 3. | 0.999 |
| gins4 | mcm2 | ENSDARP00000151126 | ENSDARP00000133012 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | DNA helicase; Belongs to the MCM family. | 0.989 |
| gins4 | mcm7 | ENSDARP00000151126 | ENSDARP00000132487 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.990 |
| gins4 | rpa1 | ENSDARP00000151126 | ENSDARP00000029067 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. | Replication protein A 70 kDa DNA-binding subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.974 |
