STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trhrbThyrotropin-releasing hormone receptor b; Belongs to the G-protein coupled receptor 1 family. (399 aa)    
Predicted Functional Partners:
trh
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems; Belongs to the TRH family.
     
 0.994
gnaq
Guanine nucleotide-binding protein (G protein), q polypeptide.
    
 0.725
gna11b
Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class).
    
 0.692
gna14a
Guanine nucleotide-binding protein (G protein), alpha 14a.
    
 0.692
gna15.4
Guanine nucleotide-binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.
    
  0.685
gna15.1
Guanine nucleotide-binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1.
    
  0.685
gna14
Guanine nucleotide-binding protein (G protein), alpha 14.
    
  0.685
nudcd1
NudC domain-containing protein 1.
      
 0.593
thraa
Thyroid hormone receptor alpha-A; High affinity receptor for triiodothyronine (By similarity). In the absence of thyroid hormone during late blastula stage development, acts as a transcriptional repressor. Whereas in the presence of thyroid hormone, can act as an activator of transcription. In addition, represses retinoic acid (RA)-signaling during blastula and gastrula stages of development; Belongs to the nuclear hormone receptor family. NR1 subfamily.
   
  
 0.575
thrab
Thyroid hormone receptor alpha b.
   
  
 0.560
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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