node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ccdc22 | ccdc93 | ENSDARP00000090542 | ENSDARP00000059573 | Coiled-coil domain-containing protein 22; May be involved in regulation of NF-kappa-B signaling. May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity). | Coiled-coil domain-containing 93. | 0.998 |
ccdc22 | commd1 | ENSDARP00000090542 | ENSDARP00000091561 | Coiled-coil domain-containing protein 22; May be involved in regulation of NF-kappa-B signaling. May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity). | Copper metabolism (Murr1) domain-containing 1. | 0.980 |
ccdc22 | commd2 | ENSDARP00000090542 | ENSDARP00000015280 | Coiled-coil domain-containing protein 22; May be involved in regulation of NF-kappa-B signaling. May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity). | COMM domain-containing 2. | 0.967 |
ccdc22 | commd3 | ENSDARP00000090542 | ENSDARP00000066763 | Coiled-coil domain-containing protein 22; May be involved in regulation of NF-kappa-B signaling. May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity). | COMM domain-containing 3. | 0.927 |
ccdc22 | commd4 | ENSDARP00000090542 | ENSDARP00000110023 | Coiled-coil domain-containing protein 22; May be involved in regulation of NF-kappa-B signaling. May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity). | COMM domain-containing 4. | 0.924 |
ccdc22 | commd6 | ENSDARP00000090542 | ENSDARP00000117302 | Coiled-coil domain-containing protein 22; May be involved in regulation of NF-kappa-B signaling. May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity). | COMM domain-containing 6. | 0.940 |
ccdc22 | snx27b | ENSDARP00000090542 | ENSDARP00000011221 | Coiled-coil domain-containing protein 22; May be involved in regulation of NF-kappa-B signaling. May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity). | Sorting nexin family member 27. | 0.518 |
ccdc22 | vps26c | ENSDARP00000090542 | ENSDARP00000033509 | Coiled-coil domain-containing protein 22; May be involved in regulation of NF-kappa-B signaling. May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity). | VPS26 endosomal protein sorting factor C. | 0.955 |
ccdc22 | vps29 | ENSDARP00000090542 | ENSDARP00000092020 | Coiled-coil domain-containing protein 22; May be involved in regulation of NF-kappa-B signaling. May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity). | Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. Retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) (By similarity). Acts also as component of the retriever complex. The retriever complex is an heterotrimeric complex related to retromer cargo-selective com [...] | 0.860 |
ccdc22 | vps35l | ENSDARP00000090542 | ENSDARP00000052536 | Coiled-coil domain-containing protein 22; May be involved in regulation of NF-kappa-B signaling. May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity). | VPS35 endosomal protein sorting factor-like; Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrins. The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins ass [...] | 0.957 |
ccdc93 | ccdc22 | ENSDARP00000059573 | ENSDARP00000090542 | Coiled-coil domain-containing 93. | Coiled-coil domain-containing protein 22; May be involved in regulation of NF-kappa-B signaling. May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity). | 0.998 |
ccdc93 | commd1 | ENSDARP00000059573 | ENSDARP00000091561 | Coiled-coil domain-containing 93. | Copper metabolism (Murr1) domain-containing 1. | 0.968 |
ccdc93 | commd2 | ENSDARP00000059573 | ENSDARP00000015280 | Coiled-coil domain-containing 93. | COMM domain-containing 2. | 0.858 |
ccdc93 | commd3 | ENSDARP00000059573 | ENSDARP00000066763 | Coiled-coil domain-containing 93. | COMM domain-containing 3. | 0.841 |
ccdc93 | commd4 | ENSDARP00000059573 | ENSDARP00000110023 | Coiled-coil domain-containing 93. | COMM domain-containing 4. | 0.814 |
ccdc93 | commd6 | ENSDARP00000059573 | ENSDARP00000117302 | Coiled-coil domain-containing 93. | COMM domain-containing 6. | 0.910 |
ccdc93 | snx27b | ENSDARP00000059573 | ENSDARP00000011221 | Coiled-coil domain-containing 93. | Sorting nexin family member 27. | 0.588 |
ccdc93 | vps26c | ENSDARP00000059573 | ENSDARP00000033509 | Coiled-coil domain-containing 93. | VPS26 endosomal protein sorting factor C. | 0.953 |
ccdc93 | vps29 | ENSDARP00000059573 | ENSDARP00000092020 | Coiled-coil domain-containing 93. | Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. Retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) (By similarity). Acts also as component of the retriever complex. The retriever complex is an heterotrimeric complex related to retromer cargo-selective com [...] | 0.909 |
ccdc93 | vps35l | ENSDARP00000059573 | ENSDARP00000052536 | Coiled-coil domain-containing 93. | VPS35 endosomal protein sorting factor-like; Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrins. The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins ass [...] | 0.942 |