STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gatmGlycine amidinotransferase, mitochondrial; Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development (By similarity) (422 aa)    
Predicted Functional Partners:
gamt
Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Important in nervous system development; Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family
   
 
 0.999
gnmt
Glycine N-methyltransferase
     
 0.941
arg2
Arginase-2, mitochondrial; Arginase, type II
    
 0.940
arg1
Arginase-1; Arginase, liver
    
 0.940
sardh
Sarcosine dehydrogenase, mitochondrial; Sarcosine dehydrogenase
    
 0.940
dao.3
D-amino-acid oxidase, tandem duplicate 3
  
 
 0.937
dao.2
D-amino-acid oxidase, tandem duplicate 2
  
 
 0.937
dao.1
D-amino-acid oxidase, tandem duplicate 1
  
 
 0.937
tha1
Threonine aldolase 1
    
  0.917
alas1
5-aminolevulinate synthase, nonspecific, mitochondrial; 5-aminolevulinate synthase; Aminolevulinate, delta-, synthetase 1
    
 0.915
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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