STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
c3a.1Complement component c3a, duplicate 1. (1643 aa)    
Predicted Functional Partners:
A9C4A2_DANRE
Si:ch73-237c6.1.
   
 0.957
cfp
Complement factor properdin.
   
 0.952
c5
Complement component 5.
   
0.934
c9
Complement component 9.
   
 
 0.784
F1QJB3_DANRE
Si:ch1073-280e3.1; Belongs to the peptidase S1 family.
   
 
 0.746
cfb
Complement factor B; Belongs to the peptidase S1 family.
   
 
 0.732
itih6
Inter-alpha-trypsin inhibitor heavy chain family member 6.
   
 
 0.632
C3AR1
C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family.
    
 
 0.607
uqcrc2a
Ubiquinol-cytochrome c reductase core protein 2a.
   
  
 0.606
apoa2
Apolipoprotein A-II.
   
  
 0.604
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.