Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
tcn2Transcobalamin II. (423 aa)    
Predicted Functional Partners:
tcnba
Similar to Transcobalamin-1 (Transcobalamin I) (TCI) (TC I).
      
 0.956
cubn
Cubilin (intrinsic factor-cobalamin receptor).
    
 0.934
amn
Amnion-associated transmembrane protein.
      
 0.931
tcnbb
Transcobalamin beta b.
   
  
 0.846
lmbrd1
Probable lysosomal cobalamin transporter; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity); Belongs to the LIMR family. LMBRD1 subfamily.
      
 0.762
ldlrap1b
Low density lipoprotein receptor adaptor protein 1b.
     
  0.700
igfn1.4
Immunoglobulin-like and fibronectin type III domain-containing 1, tandem duplicate 4.
    
 
 0.685
gspt1
G1 to S phase transition 1.
   
  
 0.680
gspt1l
G1 to S phase transition 1,-like.
   
  
 0.669
igfn1.3
Immunoglobulin-like and fibronectin type III domain-containing 1, tandem duplicate 3.
    
 
 0.666
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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