STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbr1Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (276 aa)    
Predicted Functional Partners:
ptgesl
Prostaglandin E synthase 2; Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2); Belongs to the GST superfamily.
   
 
 0.940
dhfr
Dihydrofolate reductase.
   
 
 0.934
ptges3a
Prostaglandin E synthase 3a (cytosolic).
   
 0.927
spra
Sepiapterin reductase a.
     
 0.923
cyp1a
Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.
   
 
 0.918
akr1b1.2
Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2.
   
 
 0.917
zgc:153031
Zgc:153031.
   
 
 0.917
sprb
Sepiapterin reductase b.
     
 0.916
ptges
Microsomal prostaglandin E synthase 1.
   
 
 0.913
ptges3b
Prostaglandin E synthase 3b (cytosolic).
   
 0.905
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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