Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mhc1zbaMHC class I antigen ZBA transcript variant 1; Belongs to the MHC class I family. (398 aa)    
Predicted Functional Partners:
calr
Calreticulin.
   
 
 0.921
b2ml
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
   
 0.908
pdia7
Protein disulfide-isomerase.
   
 
  0.859
mhc1uma
Major histocompatibility complex class I UMA.
  
0.857
cd8a
CD8 antigen, alpha polypeptide.
    
 0.844
pdia3
Protein disulfide-isomerase.
   
 
  0.809
cd8b
Cd8 beta.
     
  0.808
b2m
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).
   
  0.792
mhc1ula
MHC class I antigen transcript variant 1; Belongs to the MHC class I family.
  
0.748
CCDC134
Coiled-coil domain containing 134.
      
 0.737
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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