Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
setd4SET domain-containing 4. (440 aa)    
Predicted Functional Partners:
setd9
SET domain-containing 9.
      
 0.824
atpsckmt
FATP synthase c subunit lysine N-methyltransferase.
      
 0.757
PRDM15
PR/SET domain 15.
    
 0.750
suclg2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.748
kiaa1958
Si:ch211-126i22.5.
      
 0.746
antkmt
Adenine nucleotide translocase lysine methyltransferase.
      
 0.740
mettl9
Methyltransferase-like 9.
      
 0.729
cbr1
Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.720
prdm10
PR domain zinc finger protein 10; May be involved in transcriptional regulation.
    
 0.705
get1
Tail-anchored protein insertion receptor WRB; Receptor for ASNA1/TRC40-mediated insertion of tail-anchored (TA) proteins into the ER membrane.
      
 0.696
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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