tab1 protein (Danio rerio) - STRING interaction network

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tab1

TGF-beta-activated kinase 1/MAP3K7-binding protein 1. (346 aa)

Predicted Functional Partners:

map3k7

0.999

tab2

0.999

traf6

0.999

tab3

0.999

xiap

0.995

irak4

0.990

ripk1l

0.989

tnfb

0.982

chuk

0.981

traf2b

0.981

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
chuk	irak4	ENSDARP00000013115	ENSDARP00000135636	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	Interleukin-1 receptor-associated kinase 4.	0.963
chuk	map3k7	ENSDARP00000013115	ENSDARP00000006286	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	Mitogen-activated protein kinase kinase kinase 7.	0.978
chuk	ripk1l	ENSDARP00000013115	ENSDARP00000014604	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	Receptor (TNFRSF)-interacting serine-threonine kinase 1,-like.	0.994
chuk	tab1	ENSDARP00000013115	ENSDARP00000053182	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	TGF-beta-activated kinase 1/MAP3K7-binding protein 1.	0.981
chuk	tab2	ENSDARP00000013115	ENSDARP00000019647	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; May play a role in signaling pathway. Involved in heart development.	0.993
chuk	tab3	ENSDARP00000013115	ENSDARP00000083707	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	Mitogen-activated protein kinase kinase kinase 7 interacting protein 3 like.	0.990
chuk	tnfb	ENSDARP00000013115	ENSDARP00000010728	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	Tumor necrosis factor b (TNF superfamily, member 2).	0.912
chuk	traf2b	ENSDARP00000013115	ENSDARP00000144196	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.878
chuk	traf6	ENSDARP00000013115	ENSDARP00000036715	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction.	0.998
chuk	xiap	ENSDARP00000013115	ENSDARP00000018322	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	X-linked inhibitor of apoptosis.	0.760
irak4	chuk	ENSDARP00000135636	ENSDARP00000013115	Interleukin-1 receptor-associated kinase 4.	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	0.963
irak4	map3k7	ENSDARP00000135636	ENSDARP00000006286	Interleukin-1 receptor-associated kinase 4.	Mitogen-activated protein kinase kinase kinase 7.	0.959
irak4	ripk1l	ENSDARP00000135636	ENSDARP00000014604	Interleukin-1 receptor-associated kinase 4.	Receptor (TNFRSF)-interacting serine-threonine kinase 1,-like.	0.492
irak4	tab1	ENSDARP00000135636	ENSDARP00000053182	Interleukin-1 receptor-associated kinase 4.	TGF-beta-activated kinase 1/MAP3K7-binding protein 1.	0.990
irak4	tab2	ENSDARP00000135636	ENSDARP00000019647	Interleukin-1 receptor-associated kinase 4.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; May play a role in signaling pathway. Involved in heart development.	0.990
irak4	tab3	ENSDARP00000135636	ENSDARP00000083707	Interleukin-1 receptor-associated kinase 4.	Mitogen-activated protein kinase kinase kinase 7 interacting protein 3 like.	0.974
irak4	tnfb	ENSDARP00000135636	ENSDARP00000010728	Interleukin-1 receptor-associated kinase 4.	Tumor necrosis factor b (TNF superfamily, member 2).	0.703
irak4	traf2b	ENSDARP00000135636	ENSDARP00000144196	Interleukin-1 receptor-associated kinase 4.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.831
irak4	traf6	ENSDARP00000135636	ENSDARP00000036715	Interleukin-1 receptor-associated kinase 4.	TNF receptor-associated factor 6; E3 ubiquitin-protein ligase that mediates ubiquitination of proteins. Adapter protein that seems to play a role in signal transduction.	0.999
map3k7	chuk	ENSDARP00000006286	ENSDARP00000013115	Mitogen-activated protein kinase kinase kinase 7.	Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.	0.978

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