Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cd74bCD74 molecule, major histocompatibility complex, class II invariant chain b. (198 aa)    
Predicted Functional Partners:
mhc2dab
Novel protein similar to vertebrate major histocompatibility complex class II DAB gene (Mhc2dab).
   
  
 0.607
mhc2a
Major histocompatibility complex class II integral membrane alpha chain gene.
   
  
 0.605
TCIM
Transcriptional and immune response regulator.
      
 0.595
mhc1zba
MHC class I antigen ZBA transcript variant 1; Belongs to the MHC class I family.
   
  
 0.532
mpeg1.1
Macrophage-expressed 1, tandem duplicate 1.
   
  
 0.509
nell2b
Neural EGFL-like 2b.
      
 0.504
trim35-23
Tripartite motif-containing 35-23.
      
 0.503
trim35-25
Tripartite motif-containing 35-25.
      
 0.503
ighv4-5
Immunoglobulin heavy variable 5-3.
      
 0.490
c1qc
Complement component 1, q subcomponent, C chain.
   
  
 0.482
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.