Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tmem18Transmembrane protein 18. (152 aa)    
Predicted Functional Partners:
mc4r
Melanocortin receptor 4; Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
      
 0.805
fto
FTO alpha-ketoglutarate-dependent dioxygenase.
      
 0.794
gnpda2
Glucosamine-6-phosphate isomerase.
      
 0.766
get4
Guided entry of tail-anchored proteins factor 4.
      
 0.737
pter
Phosphotriesterase-related protein.
      
 0.715
KCTD15
Potassium channel tetramerization domain containing 15.
      
 0.710
sec16b
SEC16 homolog B, endoplasmic reticulum export factor.
      
 0.696
zfp64
Zinc finger protein 64 homolog (mouse).
      
 0.684
clip1a
CAP-GLY domain-containing linker protein 1a.
      
 0.628
mtch2
Mitochondrial carrier homolog 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.604
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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