Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
tomm40lTranslocase of outer mitochondrial membrane 40 homolog,-like. (338 aa)    
Predicted Functional Partners:
tomm7
Translocase of outer mitochondrial membrane 7 homolog (yeast).
   
 0.999
tomm20b
Mitochondrial import receptor subunit TOM20 homolog B; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the tom40 translocation pore (By similarity).
   
 0.996
tomm70a
Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae).
   
 0.995
tomm22
Translocase of Outer mitochondrial membrane 22 homolog (Yeast).
   
 0.994
tomm5
Translocase of outer mitochondrial membrane 5 homolog (yeast).
    
 0.990
pink1
PTEN-induced kinase 1.
    
 0.978
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.964
timm50
Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
   
 
 0.962
tomm20a
Translocase of outer mitochondrial membrane 20.
   
 0.956
tomm6
Translocase of outer mitochondrial membrane 6 homolog (yeast).
    
 0.944
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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