Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hax1HCLS1-associated protein X-1. (286 aa)    
Predicted Functional Partners:
vps45
Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family.
      
 0.735
aqp10b
Aquaporin 10b; Belongs to the MIP/aquaporin (TC 1.A.8) family.
      
 0.686
pygo2
Pygopus homolog 2 (Drosophila).
      
 0.598
smarcd2
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily d, member 2.
      
 0.561
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
      
 0.551
clpb
Caseinolytic mitochondrial matrix peptidase chaperone subunit B.
      
 0.551
parla
Presenilins-associated rhomboid-like protein, mitochondrial; Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of opa1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptotic signals (By similarity); Belongs to the peptidase S54 family.
   
 
 0.521
HTRA2
Si:dkey-84o3.4.
    
 
 0.519
LOC799006
Si:dkey-265c15.6.
    
 
 0.516
urb2
URB2 ribosome biogenesis homolog.
      
 0.501
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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