Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ifrd2Interferon-related developmental regulator 2. (435 aa)    
Predicted Functional Partners:
ccdc124
Coiled-coil domain-containing protein 124; Required for proper progression of late cytokinetic stages.
   
  
 0.748
sipa1l1
Signal-induced proliferation-associated 1-like 1.
   
  
 0.669
serbp1a
SERPINE1 mRNA-binding protein 1a.
   
  
 0.649
commd2
COMM domain-containing 2.
    
 
 0.635
commd1
Copper metabolism (Murr1) domain-containing 1.
   
 
 0.604
esf1
ESF1, nucleolar pre-rRNA-processing protein, homolog (S. cerevisiae).
   
  
 0.598
commd6
COMM domain-containing 6.
    
 
 0.584
osbpl9
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.583
commd7
COMM domain-containing 7.
   
 
 0.553
serbp1b
SERPINE1 mRNA-binding protein 1b.
      
 0.553
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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