STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
myo1caUnconventional myosin-Ic; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). (1045 aa)    
Predicted Functional Partners:
acta1b
Actin alpha 1, skeletal muscle b.
   
 
 0.712
rcan1a
Regulator of calcineurin 1a.
   
  
 0.669
lmtk2
Lemur tyrosine kinase 2.
    
 
 0.541
calm2a
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
    
 
 0.497
phf5a
PHD finger protein 5A.
      
 0.453
glcci1a
Glucocorticoid-induced 1a.
      
 0.452
myo1b
Myosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
  
 
 
0.443
svilc
Supervillin c.
   
 
 0.428
lmod2a
Leiomodin 2 (cardiac) a.
    
 
 0.424
PLEKHH3
Si:ch211-18i17.2.
 
  
 
 0.418
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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