Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rnf24Ring finger protein 24. (149 aa)    
Predicted Functional Partners:
clrn3
Clarin 3.
      
 0.911
ubox5
U-box domain-containing 5.
    
 
 0.844
kctd9b
Potassium channel tetramerization domain-containing 9b.
      
 0.790
r3hdml
R3H domain-containing-like; Belongs to the CRISP family.
      
 0.719
LOC100536716
Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.695
vps16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
      
 0.668
Ccdc86
Si:ch211-217k17.7.
      
 0.662
fam113
Family with sequence similarity 113.
      
 0.643
rwdd1
RWD domain-containing 1.
      
 0.630
mbip
MAP3K12-binding inhibitory protein 1.
      
 0.607
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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