STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ripply3Protein ripply3; Probable transcriptional regulator involved in developmental processes; Belongs to the ripply family. (110 aa)    
Predicted Functional Partners:
hmg20a
High mobility group 20A.
      
 0.660
INSM2
INSM transcriptional repressor 2.
      
 0.551
gse1
Genetic suppressor element 1.
      
 0.540
tle3a
Transducin-like enhancer protein 3-A; Transcriptional corepressor that binds to a number of transcription factors. Enhances the transcriptional repression activity of pnx; Belongs to the WD repeat Groucho/TLE family.
    
 
 0.482
rbm45
RNA-binding motif protein 45.
      
 0.455
tbx1
T-box transcription factor TBX1; May act as a transcriptional factor. Acts cell autonomously in the pharyngeal mesendoderm and influences the development of neural crest-derived cartilages secondarily.
    
 
 0.450
bcl6ab
BCL6A transcription repressor b.
      
 0.439
tbx20
T-box transcription factor TBX20; Transcriptional regulator that may play a very early role in the differentiation of the cardiac precursors.
    
 
 0.423
irf2bpl
Interferon regulatory factor 2-binding protein-like.
      
 0.415
skap2
Src kinase-associated phosphoprotein 2; May be involved in B-cell and macrophage adhesion processes. May play a role in src signaling pathway (By similarity).
      
 0.413
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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