Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dnajc22DnaJ (Hsp40) homolog, subfamily C, member 22. (338 aa)    
Predicted Functional Partners:
lmbr1l
Limb region 1 homolog-like protein; May play a role in lymphocyte development by negatively regulating the canonical Wnt signaling pathway (By similarity). May act as a LCN1 receptor (By similarity).
   
 
 0.883
arf3a
ADP-ribosylation factor 3a; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.841
ikzf4
IKAROS family zinc finger 4.
 
  
 
 0.816
kmt2bb
Lysine (K)-specific methyltransferase 2Bb.
    
 0.794
dusp28
Dual-specificity phosphatase 28.
   
 
 0.794
dnaja2b
DnaJ heat shock protein family (Hsp40) member A2b.
   
 0.786
B8JLK9_DANRE
Si:dkey-69o16.5.
      
 0.780
dnajc5ab
DnaJ (Hsp40) homolog, subfamily C, member 5ab.
    
 0.734
dnajc5gb
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma b.
    
 0.722
kmt2cb
Lysine (K)-specific methyltransferase 2Cb.
    
 0.722
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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