Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
slc8a4bSolute carrier family 8 member 4b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (925 aa)    
Predicted Functional Partners:
prkacbb
Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily.
   
 
  0.913
prkacab
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.
   
 
  0.850
prkacaa
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
   
 
  0.850
prkacba
Protein kinase, cAMP-dependent, catalytic, beta a; Belongs to the protein kinase superfamily.
   
 
  0.815
slc25a36a
Solute carrier family 25 member 36-A.
      
 0.712
slc8a3
Solute carrier family 8 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
     
  0.638
ube2al
Ubiquitin-conjugating enzyme E2 A,-like; Belongs to the ubiquitin-conjugating enzyme family.
      
 0.595
gnl1
Guanine nucleotide-binding protein-like 1.
      
 0.594
ppp1r14ab
Protein phosphatase 1, regulatory (inhibitor) subunit 14Ab.
      
 0.594
fras1
Fraser extracellular matrix complex subunit 1.
   
  0.591
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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