rcc1 protein (Danio rerio) - STRING interaction network

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Score

rcc1

Regulator of chromosome condensation 1. (418 aa)

Predicted Functional Partners:

ran

0.985

rangap1b

0.984

RANBP2

0.984

kpnb1

0.977

ube2ia

0.969

dlgap5

0.960

nusap1

0.948

rangap1a

0.945

ranbp3b

0.944

ranbp3a

0.944

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RANBP2	kpnb1	ENSDARP00000153036	ENSDARP00000135519	Si:ch1073-55a19.2.	Karyopherin (importin) beta 1.	0.979
RANBP2	nusap1	ENSDARP00000153036	ENSDARP00000015118	Si:ch1073-55a19.2.	Nucleolar and spindle-associated protein 1; Microtubule-associated protein with the capacity to bundle and stabilize microtubules. May associate with chromosomes and promote the organization of mitotic spindle microtubules around them (By similarity).	0.939
RANBP2	ran	ENSDARP00000153036	ENSDARP00000108629	Si:ch1073-55a19.2.	GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...]	0.875
RANBP2	rangap1a	ENSDARP00000153036	ENSDARP00000083043	Si:ch1073-55a19.2.	RAN GTPase-activating protein 1a.	0.960
RANBP2	rangap1b	ENSDARP00000153036	ENSDARP00000072946	Si:ch1073-55a19.2.	Ran GTPase-activating protein 1b.	0.984
RANBP2	rcc1	ENSDARP00000153036	ENSDARP00000054025	Si:ch1073-55a19.2.	Regulator of chromosome condensation 1.	0.984
RANBP2	ube2ia	ENSDARP00000153036	ENSDARP00000052745	Si:ch1073-55a19.2.	SUMO-conjugating enzyme UBC9-B; Accepts the ubiquitin-like proteins sumo1, sumo2 and sumo3 from the uble1a-uble1b E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as ranbp2 or cbx4. Essential for nuclear architecture and chromosome segregation (By similarity). Mediates nuclear localization of vsx1. Required for progression through mitosis during organogenesis. Belongs to the ubiquitin-conjugating enzyme family.	0.989
dlgap5	kpnb1	ENSDARP00000066410	ENSDARP00000135519	Discs, large (Drosophila) homolog-associated protein 5.	Karyopherin (importin) beta 1.	0.964
dlgap5	nusap1	ENSDARP00000066410	ENSDARP00000015118	Discs, large (Drosophila) homolog-associated protein 5.	Nucleolar and spindle-associated protein 1; Microtubule-associated protein with the capacity to bundle and stabilize microtubules. May associate with chromosomes and promote the organization of mitotic spindle microtubules around them (By similarity).	0.984
dlgap5	ran	ENSDARP00000066410	ENSDARP00000108629	Discs, large (Drosophila) homolog-associated protein 5.	GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...]	0.725
dlgap5	rangap1a	ENSDARP00000066410	ENSDARP00000083043	Discs, large (Drosophila) homolog-associated protein 5.	RAN GTPase-activating protein 1a.	0.567
dlgap5	rcc1	ENSDARP00000066410	ENSDARP00000054025	Discs, large (Drosophila) homolog-associated protein 5.	Regulator of chromosome condensation 1.	0.960
kpnb1	RANBP2	ENSDARP00000135519	ENSDARP00000153036	Karyopherin (importin) beta 1.	Si:ch1073-55a19.2.	0.979
kpnb1	dlgap5	ENSDARP00000135519	ENSDARP00000066410	Karyopherin (importin) beta 1.	Discs, large (Drosophila) homolog-associated protein 5.	0.964
kpnb1	nusap1	ENSDARP00000135519	ENSDARP00000015118	Karyopherin (importin) beta 1.	Nucleolar and spindle-associated protein 1; Microtubule-associated protein with the capacity to bundle and stabilize microtubules. May associate with chromosomes and promote the organization of mitotic spindle microtubules around them (By similarity).	0.961
kpnb1	ran	ENSDARP00000135519	ENSDARP00000108629	Karyopherin (importin) beta 1.	GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP- bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment [...]	0.976
kpnb1	rangap1a	ENSDARP00000135519	ENSDARP00000083043	Karyopherin (importin) beta 1.	RAN GTPase-activating protein 1a.	0.859
kpnb1	rangap1b	ENSDARP00000135519	ENSDARP00000072946	Karyopherin (importin) beta 1.	Ran GTPase-activating protein 1b.	0.910
kpnb1	rcc1	ENSDARP00000135519	ENSDARP00000054025	Karyopherin (importin) beta 1.	Regulator of chromosome condensation 1.	0.977
kpnb1	ube2ia	ENSDARP00000135519	ENSDARP00000052745	Karyopherin (importin) beta 1.	SUMO-conjugating enzyme UBC9-B; Accepts the ubiquitin-like proteins sumo1, sumo2 and sumo3 from the uble1a-uble1b E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as ranbp2 or cbx4. Essential for nuclear architecture and chromosome segregation (By similarity). Mediates nuclear localization of vsx1. Required for progression through mitosis during organogenesis. Belongs to the ubiquitin-conjugating enzyme family.	0.667

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