STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arid5bAT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). (1050 aa)    
Predicted Functional Partners:
phf2
Lysine-specific demethylase phf2; Lysine demethylase that demethylates both histones and non- histone proteins. Mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2). Recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA (By similarity).
     
 0.974
fto
FTO alpha-ketoglutarate-dependent dioxygenase.
      
 0.668
irx3a
Iroquois 3 homeobox protein.
    
 
 0.612
washc2c
WASH complex subunit 2C.
   
  
 0.609
pnisr
PNN-interacting serine/arginine-rich protein.
   
 
 0.565
C7H16orf87
UPF0547 protein C16orf87 homolog; Belongs to the UPF0547 family.
    
 
 0.543
ube2q2
Ubiquitin-conjugating enzyme E2Q family member 2.
      
 0.540
kdm3b
Lysine (K)-specific demethylase 3B.
   
 
 0.521
jdp2b
Jun dimerization protein 2; Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins; Belongs to the bZIP family. ATF subfamily.
    
 
 0.520
pbrm1
Polybromo 1.
   
 
 0.490
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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