| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C7H16orf87 | arid5b | ENSDARP00000015462 | ENSDARP00000054091 | UPF0547 protein C16orf87 homolog; Belongs to the UPF0547 family. | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | 0.907 |
| C7H16orf87 | hdac1 | ENSDARP00000015462 | ENSDARP00000051798 | UPF0547 protein C16orf87 homolog; Belongs to the UPF0547 family. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.636 |
| C7H16orf87 | hdac8 | ENSDARP00000015462 | ENSDARP00000017858 | UPF0547 protein C16orf87 homolog; Belongs to the UPF0547 family. | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). | 0.636 |
| alpk3b | arid5b | ENSDARP00000142638 | ENSDARP00000054091 | Alpha-kinase 3b. | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | 0.609 |
| alpk3b | lyst | ENSDARP00000142638 | ENSDARP00000090212 | Alpha-kinase 3b. | Lysosomal-trafficking regulator. | 0.624 |
| arid5b | C7H16orf87 | ENSDARP00000054091 | ENSDARP00000015462 | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | UPF0547 protein C16orf87 homolog; Belongs to the UPF0547 family. | 0.907 |
| arid5b | alpk3b | ENSDARP00000054091 | ENSDARP00000142638 | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | Alpha-kinase 3b. | 0.609 |
| arid5b | fto | ENSDARP00000054091 | ENSDARP00000107656 | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | FTO alpha-ketoglutarate-dependent dioxygenase. | 0.595 |
| arid5b | hdac1 | ENSDARP00000054091 | ENSDARP00000051798 | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.624 |
| arid5b | hdac8 | ENSDARP00000054091 | ENSDARP00000017858 | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). | 0.568 |
| arid5b | irx3a | ENSDARP00000054091 | ENSDARP00000139882 | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | Iroquois 3 homeobox protein. | 0.618 |
| arid5b | lyst | ENSDARP00000054091 | ENSDARP00000090212 | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | Lysosomal-trafficking regulator. | 0.602 |
| arid5b | phf2 | ENSDARP00000054091 | ENSDARP00000045941 | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | Lysine-specific demethylase phf2; Lysine demethylase that demethylates both histones and non- histone proteins. Mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2). Recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA (By similarity). | 0.970 |
| arid5b | trps1 | ENSDARP00000054091 | ENSDARP00000137858 | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | Trichorhinophalangeal syndrome I. | 0.628 |
| arid5b | washc2c | ENSDARP00000054091 | ENSDARP00000109069 | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | WASH complex subunit 2C. | 0.600 |
| fto | arid5b | ENSDARP00000107656 | ENSDARP00000054091 | FTO alpha-ketoglutarate-dependent dioxygenase. | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | 0.595 |
| fto | irx3a | ENSDARP00000107656 | ENSDARP00000139882 | FTO alpha-ketoglutarate-dependent dioxygenase. | Iroquois 3 homeobox protein. | 0.895 |
| hdac1 | C7H16orf87 | ENSDARP00000051798 | ENSDARP00000015462 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | UPF0547 protein C16orf87 homolog; Belongs to the UPF0547 family. | 0.636 |
| hdac1 | arid5b | ENSDARP00000051798 | ENSDARP00000054091 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | AT-rich interactive domain-containing protein 5B; Transcription coactivator that binds to the 5'-AATA[CT]-3' core sequence and plays a key role in adipogenesis and liver development. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes (By similarity). | 0.624 |
| hdac1 | phf2 | ENSDARP00000051798 | ENSDARP00000045941 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Lysine-specific demethylase phf2; Lysine demethylase that demethylates both histones and non- histone proteins. Mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2). Recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA (By similarity). | 0.468 |