STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsc22d3TSC22 domain family, member 3. (143 aa)    
Predicted Functional Partners:
fkbp5
Peptidylprolyl isomerase.
   
  
 0.806
irg1l
Immunoresponsive gene 1,-like.
      
 0.584
nr1d2a
Nuclear receptor subfamily 1, group D, member 2a.
   
  
 0.583
rsrp1
Arginine/serine-rich protein 1; Belongs to the RSRP family.
      
 0.540
otud4
OTU deubiquitinase 4.
      
 0.540
nrbp1
Nuclear receptor-binding protein 1.
    
 
 0.539
sgk1
Serine/threonine-protein kinase Sgk1; Protein kinase that may play an important role in cellular stress response. May be involved in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion (By similarity); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
   
 
 0.513
klf9
Kruppel-like factor 9.
   
 
 0.511
ss18l2
Zgc:112097 protein.
      
 0.509
zbtb16a
Zinc finger and BTB domain-containing protein 16-A; Probable transcription factor. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Inhibits neurogenesis. Belongs to the krueppel C2H2-type zinc-finger protein family.
   
 
 0.503
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.