Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
gpr137G protein-coupled receptor 137. (375 aa)    
Predicted Functional Partners:
slc52a2
Solute carrier family 52 member 2.
      
 0.890
gpr157
G protein-coupled receptor 157.
      
 0.800
LOC556363
G protein-coupled receptor 108.
      
 0.780
gpr107
G protein-coupled receptor 107.
      
 0.780
paqr5a
Membrane progestin receptor gamma-A; Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation (By similarity); Belongs to the ADIPOR family.
      
 0.719
p2ry8
P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family.
      
 0.594
paqr7b
Membrane progestin receptor alpha-B; Steroid membrane receptor. Signals upon progestin binding, resulting in rapid activation of MAPK and down-regulation of adenylyl cyclase activity. Interacts with steroids with varying degrees of affinity, showing specificity for activation by the maturation-inducing steroid (MIS) 4-pregnen-17,20beta-diol-3-one (17,20beta-DHP). Capable of mediating progestin-induced oocyte maturation.
      
 0.574
paqr8
Progestin and adipoQ receptor family member VIII.
      
 0.562
gpr143
G protein-coupled receptor 143.
      
 0.556
aldh18a1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
      
 0.473
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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