Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mipaMajor intrinsic protein of lens fiber 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)    
Predicted Functional Partners:
aqp10b
Aquaporin 10b; Belongs to the MIP/aquaporin (TC 1.A.8) family.
     
 0.886
aqp11
Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
     
 0.868
mipb
Major intrinsic protein of lens fiber b; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
0.831
prkacab
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.
   
 0.817
prkacba
Protein kinase, cAMP-dependent, catalytic, beta a; Belongs to the protein kinase superfamily.
   
 0.817
cryaa
Crystallin, alpha A; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.796
BFSP1
Beaded filament structural protein 1.
      
 0.782
bfsp2
Beaded filament structural protein 2, phakinin; Belongs to the intermediate filament family.
   
 
 0.771
aqp12
Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
     
 0.709
Aqp9a
Uncharacterized protein.
      
 0.693
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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