Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
E7F704_DANRESi:ch1073-272o11.3. (563 aa)    
Predicted Functional Partners:
tchp
Trichoplein keratin filament-binding protein; May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (By similarity). Belongs to the TCHP family.
    
   0.877
cdt1
Chromatin licensing and DNA replication factor 1.
   
   0.665
rrbp1b
Ribosome-binding protein 1b.
    
   0.628
rrbp1a
Ribosome-binding protein 1a.
    
   0.628
igsf3
Immunoglobulin superfamily, member 3.
    
   0.560
LOC100005927
Uncharacterized protein.
    
   0.560
zgc:91849
Zgc:91849.
    
   0.560
fgfr1op2
FGFR1 oncogene partner 2 homolog.
    
   0.550
SIKE1
Im:6912630.
    
   0.550
cbsa
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
      
 0.545
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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