STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dennd2bSuppression of tumorigenicity 5. (1132 aa)    
Predicted Functional Partners:
rab9b
RAB9B, member RAS oncogene family.
      
 0.799
trarg1b
Trafficking regulator of GLUT4 (SLC2A4) 1b.
      
 0.689
rab9a
RAB9A, member RAS oncogene family.
      
 0.669
rab13
Ras-related protein Rab-13; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in endocytic recycling and may regulate the transport to the plasma membrane of transmembrane proteins. May regulate the assembly and the activity of tight jun [...]
      
 0.661
dennd1b
DENN/MADD domain-containing 1B.
   
 
 0.629
rab15
RAB15, member RAS oncogene family.
      
 0.588
st13
Suppression of tumorigenicity 13 (Colon carcinoma) (Hsp70 interacting protein).
      
 0.588
micall2a
Mical-like 2a.
      
 0.565
zgc:101699
Zgc:101699.
      
 0.546
steap2
STEAP family member 2, metalloreductase.
      
 0.514
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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