Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
foxb2Forkhead box B2. (313 aa)    
Predicted Functional Partners:
lrtm1
Leucine-rich repeats and transmembrane domains 1.
      
 0.682
sox5
SRY-box transcription factor 5.
      
 0.571
hoxc5a
Homeobox protein Hox-C5a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
    
 
 0.562
prune2
Prune homolog 2 with BCH domain.
      
 0.466
cep78
Centrosomal protein 78.
      
 0.463
pou2f3
POU domain protein.
      
 0.449
vps13a
Vacuolar protein sorting 13 homolog A.
      
 0.447
ostf1
Osteoclast-stimulating factor 1; Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.
      
 0.443
ntm
Neurotrimin.
      
 0.442
prdm16
Si:ch211-263k4.2.
      
 0.436
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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