STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccnqCyclin-Q; May be an activating cyclin for the cyclin-associated kinase CDK10. (247 aa)    
Predicted Functional Partners:
cdk10
Cyclin-dependent kinase 10; Belongs to the protein kinase superfamily.
   
 
 0.834
cdk9
Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.
   
 
 0.769
cdk13
Cyclin-dependent kinase 13.
   
 
 0.751
cdk12
Cyclin-dependent kinase 12.
   
 
 0.738
pkn2
Serine/threonine-protein kinase N2.
   
 
 0.673
supt5h
Transcription elongation factor SPT5; May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. Probably enhances transcriptional pausing at sites proximal to the promoter, which may facilitate the assembly of an elongation competent RNA polymerase II complex. Also acts to stimulate transcriptional elongation at low nucleotide concentrations. Regulation of transcriptional elongation by this protein is required for the expression of genes which control neuronal development. Belongs to the SPT [...]
   
 
 0.572
hexim1
Protein HEXIM; Probable transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor; Belongs to the HEXIM family.
   
 
 0.567
noc4l
Nucleolar complex protein 4 homolog.
      
 0.557
dpy19l3
Dpy-19-like C-mannosyltransferase 3.
      
 0.556
ddb1
Damage-specific DNA-binding protein 1.
    
 
 0.535
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.