Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
nkx3-2Bagpipe homeobox transcription factor Bapx1. (245 aa)    
Predicted Functional Partners:
pax9
Paired box 9.
   
 
 0.801
hand2
Heart- and neural crest derivatives-expressed protein 2; Essential for myocardial and pectoral fin differentiation, patterning and morphogenesis.
   
 
 0.784
edn1
Endothelin 1.
      
 0.741
gdf5
Growth differentiation factor 5.
      
 0.720
pax1a
Paired box 1a.
    
 
 0.613
ednraa
Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.
      
 0.599
foxf2b
Forkhead box F2b.
   
 
 0.599
col2a1a
Collagen, type II, alpha 1a.
   
 
 0.597
bod1l1
Biorientation of chromosomes in cell division 1-like 1.
      
 0.590
pax1b
Paired box 1b.
    
 
 0.585
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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