STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nkx3-2Bagpipe homeobox transcription factor Bapx1. (245 aa)    
Predicted Functional Partners:
pax9
Paired box 9.
   
  
 0.845
hand2
Heart- and neural crest derivatives-expressed protein 2; Essential for myocardial and pectoral fin differentiation, patterning and morphogenesis.
   
 
 0.794
edn1
Endothelin 1.
   
  
 0.754
gdf5
Growth differentiation factor 5.
      
 0.751
ednraa
Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.
      
 0.670
pax1a
Paired box 1a.
      
 0.624
barx1
Homeobox protein BarH-like 1; Transcription factor, is involved in craniofacial development, and in stomach organogenesis; Belongs to the BAR homeobox family.
   
  
0.611
col2a1a
Collagen, type II, alpha 1a.
   
 
 0.608
foxf2b
Forkhead box F2b.
   
 
 0.599
sox9a
HMG box transcription factor Sox9a.
   
 
 0.595
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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