Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ap1s2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)    
Predicted Functional Partners:
ap1g2
AP-1 complex subunit gamma.
    
 0.990
ap1m1
AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
    
 0.981
ap1m2
AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
    
 0.970
ap1g1
AP-1 complex subunit gamma.
    
 0.969
ap1m3
Adaptor-related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family.
    
  0.967
ap1b1
AP complex subunit beta.
   
 0.951
ap1s3b
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
  
  
0.945
ap1s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
  
  
0.919
LOC110438225
Clat_adaptor_s domain-containing protein.
    
  0.904
AP1S2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
     
  0.868
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.