Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
npm1bNucleophosmin 1b. (329 aa)    
Predicted Functional Partners:
ncl
Nucleolin.
   
 
 0.956
rpl23a
Ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family.
   
   0.918
rpl4
Ribosomal protein L4.
   
 
 0.912
rpl6
Ribosomal protein L6.
   
 
 0.905
rpl5b
Ribosomal protein L5b.
   
 
 0.897
rpl5a
Ribosomal protein L5a.
   
 
 0.878
rps6
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
   
 
 0.877
rpl35
60S ribosomal protein L35; Plays an essential role in early embryonic development. May act as a haploinsufficient tumor suppressor. Belongs to the universal ribosomal protein uL29 family.
   
   0.863
rpl19
60S ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.
   
   0.861
rpl14
Ribosomal protein L14.
   
   0.857
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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