Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uncx4.1Homeobox protein unc-4 homolog; Transcription factor involved in somitogenesis and neurogenesis; Belongs to the paired homeobox family. Unc-4 subfamily. (470 aa)    
Predicted Functional Partners:
Alx3
Uncharacterized protein.
   
  
 0.824
mespab
Mesoderm posterior ab.
    
 
 0.803
otpa
Orthopedia homeobox a.
   
  
0.761
otpb
Homeobox protein orthopedia B; Involved in the specification of isotocin cells. Required for the specification of dopaminergic neurons in the developing hypothalamus and posterior tuberculum; Belongs to the paired homeobox family. Bicoid subfamily.
   
  
0.761
tbx6
T-box transcription factor TBX6; T-box transcription factor involved in the development of paraxial mesoderm.
    
 
 0.729
lfng
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Involved in the correct formation of boundaries in the somites and hindbrain (By similarity). Required for Delta-Notch-mediated induction of hypochord cells at the lateral borders of the midline precursor domain.
    
 
 0.726
tbx18
T-box transcription factor 18.
    
 
 0.701
tbx16l
T-box transcription factor TBX6L; Probable transcriptional regulator involved in developmental processes.
    
 
 0.693
pax1b
Paired box 1b.
    
 
 0.673
her1
Hairy-related 1.
    
 
 0.664
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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