Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lgals3bpaGalectin-3-binding protein A; Promotes integrin-mediated cell adhesion. (567 aa)    
Predicted Functional Partners:
il12rb2l
Interleukin 12 receptor, beta 2a,-like.
    
 0.800
wipf1a
WAS/WASL-interacting protein family, member 1a.
      
 0.782
hcst
Hematopoietic cell signal transducer.
      
 0.719
cmklr1l1
Chemokine-like receptor 1 like 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.688
il12ba
Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.
    
 0.626
lgals9l3
Galectin.
   
 
 0.623
ccl35.2
Chemokine (C-C motif) ligand 35, duplicate 2.
      
 0.596
sqleb
Squalene epoxidase b.
      
 0.595
ccl19a.1
C-C motif chemokine.
   
  
 0.518
LOC101882206
MARVEL domain-containing protein.
      
 0.504
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (18%) [HD]