Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
osr2Protein odd-skipped-related 2; Transcriptional repressor (By similarity). Required for pronephric kidney development; Belongs to the Odd C2H2-type zinc-finger protein family. (238 aa)    
Predicted Functional Partners:
fam20b
Glycosaminoglycan xylosylkinase; Responsible for the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature GAG chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases (By similarity). Belongs to the FAM20 family.
      
 0.735
pax9
Paired box 9.
    
 
 0.676
msx1a
Muscle segment homeobox 1a.
    
 
 0.634
barx1
Homeobox protein BarH-like 1; Transcription factor, is involved in craniofacial development, and in stomach organogenesis; Belongs to the BAR homeobox family.
    
 0.600
triobpa
TRIO and F-actin-binding protein a.
      
 0.581
tbx22
T-box transcription factor 22.
      
 0.560
fgf8a
Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis.
    
 
 0.551
ralgps1
Ras-specific guanine nucleotide-releasing factor RalGPS1; Guanine nucleotide exchange factor. May be involved in cytoskeletal organization.
    
 
 0.517
Fnip2
Si:ch211-42i9.8.
    
 
 0.516
zmynd11
Zinc finger, MYND-type-containing 11.
    
 
 0.503
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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