Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cbln14Cerebellin 14. (225 aa)    
Predicted Functional Partners:
lrfn1
Leucine-rich repeat and fibronectin type III domain-containing protein 1; Involved in the regulation of excitatory synapses.
    
 
 0.746
lrrtm1
Leucine-rich repeat transmembrane neuronal 1.
    
 
 0.567
sparcl1
Secreted acidic cysteine rich glycoprotein-like.
    
 
 0.562
ptprsb
Protein tyrosine phosphatase receptor type Sa.
      
 0.559
sparc
Secreted protein, acidic, cysteine-rich (osteonectin).
   
 
 0.518
fgf22
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 
 0.470
fam78ab
Family with sequence similarity 78 member Ab.
  
 
   0.460
fam78aa
Family with sequence similarity 78 member Aa.
  
 
   0.459
fam78ba
Family with sequence similarity 78 member Ba.
  
 
   0.457
ptprfb
Receptor-type tyrosine-protein phosphatase F; Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) (By similarity). Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
      
 0.444
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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