Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gh1Growth hormone 1. (210 aa)    
Predicted Functional Partners:
ghra
Growth hormone receptor a.
    
 0.996
ghrb
Growth hormone receptor b.
    
 0.985
smtlb
Somatolactin beta.
   
 
0.975
ghrl
Ghrelin/obestatin prepropeptide.
   
 
 0.946
prlra
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily.
   
 0.942
prl
Prolactin.
   
0.884
smtla
Somatolactin alpha.
     
 0.875
pomca
Pro-opiomelanocortin protein.
   
  
 0.863
prl2
Prolactin 2.
   
0.823
lepr
Leptin receptor.
   
 
 0.787
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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